Screening of 100 women for HPV infection and HPV genotyping

Cervical human papillomavirus (HPV) infection in South African women: implications for HPV screening and vaccine strategies.

The prevalence of cervical human papillomavirus (HPV) in South African women (n = 1,073) increased from 20.4% (173/848) in women with normal cytology to 41.7% (48/115) in women with atypical squamous cells of undetermined significance, 70.2% (40/57) in women with low-grade squamous intraepithelial lesions, and 83% (44/53) in women with high-grade squamous intraepithelial lesions (HSILs). HPV ty...

HPV infection and HPV-associated neoplasia in immunocompromised women

Prevalence of human papillomavirus (HPV), distribution of HPV types, and risk factors for infection in HPV-positive women.

The aim of this study was to describe the prevalence of human papillomavirus (HPV), the distribution of different HPV types, and the putative risk factors for infection among HPV-positive women from the State of Alagoas, Northeast Brazil. We analyzed data from 515 patients attending public and private health centers. HPV DNA from cervical samples was extracted and HPV genotyping was performed b...

Clinical utility of HPV genotyping.

Cervical cancer screening is presently done by finding abnormal cells in cervical smears (i.e., cervical cytology or Pap smears). However, cervical cytology is not full-proof. Cervical cytology is insensitive for the detection of cancer and precancer [1], requiring many rounds of screening to achieve programmatic effectiveness. It is now recognized that virtually all cervical cancers, both of t...

Can human papillomavirus (HPV) genotyping classify non-16/18 high-risk HPV infection by risk stratification?

OBJECTIVE Infection with high-risk genotypes of human papillomavirus (HR-HPV) is the major cause of invasive cervical cancers. HPV-16 and HPV-18 are known to be responsible for two-thirds of all invasive cervical carcinomas, followed by HPV-45, -31, and -33. Current guidelines only differentiate HPV-16/18 (+) by recommending direct colposcopy for treatment. We tried to evaluate whether there ar...